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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease

Somenath Datta, Brett M. Antonio, Nathan H. Zahler, Jonathan W. Theile, Doug Krafte, Hengtao Zhang, Paul B. Rosenberg, Alec B. Chaves, Deborah M. Muoio, Guofang Zhang, Daniel Silas, Guojie Li, Karen Soldano, Sarah Nystrom, Davis Ferreira, Sara E. Miller, James R. Bain, Michael J. Muehlbauer, Olga Ilkayeva, Thomas C. Becker, Hans-Ewald Hohmeier, Christopher B. Newgard,


Aaron Gerlach, PhD

Aaron Gerlach, Ph.D., serves as our Director of Drug Discovery Alliances. He has been with Icagen since 2003, serving as a project lead for internal and collaborative research partnerships in addition to contributing to the development of Icagen’s business opportunities. Dr. Gerlach brings more than 25 years of ion channel target expertise and over 20


Chris Silvia, PhD

Chris Silvia has more than 25 years of experience in the pharmaceutical and biotech industries. He began his employment with Icagen in Molecular Biology and Biochemistry, where he cloned and expressed ion channels and holds several patents related to ion channel molecular biology. Dr. Silvia has had increasing levels of responsibility in the information technology

Mark Chapman, PhD

Mark Chapman joined Icagen in 2000 and is currently a member of the leadership team. He has a great depth of expertise in ion channel biology and has led multiple internal drug discovery projects as well as programs with pharmaceutical partners. Dr. Chapman received a Doctorate of Pharmacology from Duke University and followed that with

Brett Antonio

Brett Antonio is currently Director of Biology and joined Icagen in 2000 following jobs at Novalon and Cubist Pharmaceuticals. He is a member of the Icagen leadership team and responsible for managing many aspects of biological assay development and execution, including HTS, plate-based pharmacology, molecular biology and cell culture. Mr. Antonio received his Bachelor of

Neil Castle, PhD

Neil Castle, PhD, has served as Icagen’s Vice President of Biology/Research since March 2016 and is a member of the senior leadership team overseeing the company’s biology activities. Prior to 2015, Icagen was part of Pfizer’s Neuroscience and Pain Research Unit, where Dr. Castle was Director of Biology and a member of the Pain Research

Anil Nair, PhD

Anil Nair joined Icagen in 2016 following a successful career at Sanofi, which began in 2001. During this time, Dr. Nair had positions of increasing responsibility including Global Coordinator for Structure, Design and Informatics. He is a member of the leadership team and coordinates all activities in computational chemistry, medicinal chemistry and in silico drug

Shetaun Deering, MBA

Shetaun Deering began her career with Icagen in July 1997. She assumed the position of Director of Operations in April 2020 and is a key member of the senior management team. Ms. Deering oversees high-level human resources duties, evaluating and continuously improving organizational policies and procedures to increase productivity and efficiency. In addition, Ms. Deering

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